Extracellular Vesicle-based Drug Delivery and Regenerative Medicine

At the Vinmec–VinUni Institute of Immunology (VIVI), researchers are advancing regenerative medicine and targeted therapies through extracellular vesicle (EV)-based technologies. Derived from mesenchymal stem cells, EVs show strong therapeutic potential comparable to stem cells, particularly in tissue repair and regeneration. Current studies demonstrate that EVs can accelerate wound healing by promoting angiogenesis, enhancing fibroblast migration, and stimulating extracellular matrix formation. Beyond regeneration, the team is developing EVs as precise drug delivery systems by encapsulating therapeutic agents and engineering their surfaces with targeting peptides to improve tissue specificity. This approach is being applied to innovative treatments for non-small cell lung cancer using miRNA-loaded EVs. Complementary projects include biomarker discovery for cancer diagnostics, herbal-exosome therapies for chronic wounds, and the V-SNIP initiative to develop plant-based treatments for snakebite envenomation. Together, these efforts highlight VinUni’s commitment to translating cutting-edge biomedical research into impactful healthcare solutions.

Read more at: https://vivi.vinuni.edu.vn/project/extracellular-vesicle-based-drug-delivery-and-regenerative-medicine/